产品货号：
Z35157
中文名称：
P27/KIP1/CDKN1B抗体
英文名称：
Anti-P27/KIP1/CDKN1B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-P27/KIP1/CDKN1B Antibody |
| 指标别名 | CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;P27;KIP1;P27KIP1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | CDKN1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human p27 KIP 1 |
| 实际分子量 | 27KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | P27(kip1),also known as cyclin dependent kinase inhibitor 1B(CDKN1B),is a major target of AFX-like forkhead proteins.CDKN1B(p27) belongs to the Cip/Kip family and functions as an important cell cycle gatekeeper.Phosphorylation leads to the ubiquitination and degradation of CDKN1B.P27(kip1) mapped to 12p13.An increase in p27 causes proliferating cells to exit from the cell cycle,and a decrease in p27 is necessary for quiescent cells to resume division.Abnormally low amounts of p27 are associated with pathological states of excessive cell proliferation,especially cancers.Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells. |
| Uniprot ID | P46527 |
| 基因名全称 | Cyclin-dependent kinase inhibitor 1B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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